Alfonso Iorio

Alfonso Iorio

MD (Perugia)

Associate Professor, Department of Clinical Epidemiology and Biostatistics
Joint Member, Department of Medicine
Attending Staff, Hamilton Health Sciences
Associate Editor, Cystic Fybrosis and Genetic Disorders Group, Cochrane Collaboration
Associate Editor, Internal and Emergency Medicine
Steering Committee Member, Italian Registry of Congenital Coagulopathies

 905.525.9140 x 22421


DeGroote School of Medicine
McMaster University
1280 Main Street West
Hamilton, Ontario, Canada
L8S 4K1

Office location: CRL-140

Administrative Assistant: Linda Sheridan
 905.525.9140 x 20152

Academic Interests

Current research interests:  Knowledge translation research and medical informatics, focused on assessment of impact of knowledge dissemination through information technology and web-based systems. Systematic review methodology, particularly applied to individual patient databases and prognostic questions.

Clinical interests: thrombosis and haemostasis, particularly recurrent VTE and epidemiology of hemophilias.

Dr Iorio is currently accepting Graduate Students.

Selected Publications

1.       A Iorio, E Oliovecchio, M Morfini and PM Mannucci on behalf of the Association of Italian Hemophilia Centres Directors. Italian Registry of Haemophilia and Allied Disorders. Objectives, methodology and data analysis. Haemophilia 2008, 14: 444–453.

2.       A Iorio and M Marcucci. Clinical trials and haemophilia: does the Bayesian approach make the ideal and desirable good friends? Haemophilia 2009; 15: 900-3

3.       A Iorio, W Ageno, B Cosmi, D Imberti, F Lussana, S Siragusa, D Tormene, A Tosetto, M Cattaneo. Guidelines of the Italian Society for Haemostasis and Thrombosis: Objectives and methodology. Thromb Res 2009;124(5):e1-5

4.       A Iorio, G Fabbriciani, M Marcucci, M Brozzetti, P Filipponi. Bone mineral density in hemophilia patients. A meta-analysis. Thrombosis and Haemostasis, 2010, 103(3):596-603.

5.       Iorio A, Marchesini E, Awad T, Gluud LL. Antiviral treatment for chronic hepatitis C in patients with human immunodeficiency virus. Cochrane Database Syst Rev 2010 Jan 20(1):CD004888

6.       Iorio A, Basileo M, Marcucci M, Guercini F, Camilloni B, Paccamiccio E, Vecchioli M, Iorio AM. No interaction between influenza vaccination and vitamin K antagonist treatment: A placebo controlled, randomized, double-blind, cross-over study. Archives of Internal Medicine, 2010, 170(7);609-16

7.       A Macura, I Abraha, J Kirkham, GF Gensini, L Moja, A Iorio. Selective outcome reporting –Telling and detecting true lies: The state of the science. Internal and Emergency Medicine, 2010, 5(2):151-5.

8.       Iorio A, Halimeh S, Holzhauer S, Goldenberg N, Marchesini E, Marcucci M, Young G, Bidlingmaier C, Brandao LR, Ettingshausen CE, Gringeri A, Kenet G, Knöfler R, Kreuz W, Kurnik K, Manner D, Santagostino E, Mannucci PM, Nowak-Göttl U. Rate of inhibitor development in previously untreated hemophilia A patients treated with plasma-derived or recombinant factor VIII concentrates: a systematic review. J Thromb Haemost. 2010 Jun;8(6):1256-65.

9.       Iorio A, Kearon C, Filippucci E, Marcucci M, Macura A, Pengo V, Siragusa S, Palareti G. Risk of recurrence after a first episode of symptomatic venous thromboembolism provoked by a transient risk factor: a systematic review. Arch Intern Med. 2010 Oct 25;170(19):1710-6.

10.     Douketis J, Tosetto A, Marcucci M, Baglin T, Cushman M, Eichinger S, Palareti G, Poli D, Tait RC, Iorio A. Patient-level meta-analysis: effect of measurement timing, threshold, and patient age on ability of D-dimer testing to assess recurrence risk after unprovoked venous thromboembolism. Ann Intern Med. 2010 Oct 19;153(8):523-31.

11.     Kearon C, Iorio A, Palareti G; Subcommittee on Control of Anticoagulation of the SSC of the ISTH. Risk of recurrent venous thromboembolism after stopping treatment in cohort studies: recommendation for acceptable rates and standardized reporting. J Thromb Haemost. 2010 Oct;8(10):2313-5.

12.     Iorio A, Matino D, D'Amico R, Makris M. Recombinant Factor VIIa concentrate versus plasma derived concentrates for the treatment of acute bleeding episodes in people with haemophilia and inhibitors. Cochrane Database Syst Rev. 2010 Aug 4;(8):CD004449.

Lab Profiles

Nima Vaezzadeh, PhD Candidate
Ran Ni, PhD Candidate
Shana Aadl Shaya, MSc Candidate

Lab Profiles

Kim Nagel, Clinical Research Coordinator
Helen Atkinson, Research Assistant
Netnapha Paredes, Research Assistant
Laura Calvert, MSc Candidate
Gabriela Chang, MSc Candidate
Sajjad Afraz, MSc Candidate