Frederick Spencer

Frederick Spencer


Professor, Department of Medicine, Division of Cardiology
Director, Thromboembolism Unit, McMaster site


Dr. Frederick Spencer received his medical degree from McGill University in 1991. He completed his internal medicine residency at the New England Medical Center (Boston, MA) in 1994 and a cardiology fellowship at the University of Massachusetts Medical Center (Worcester, MA) in 1997. He then joined the faculty at the University of Massachusetts Medical Center where he served as Director of the Coronary Care Unit as well as of the Anticoagulation Services and the Cardiac Rehabilitation Center. In 2005, he joined the Faculty of Medicine at McMaster University in the Divisions of Hematology/Thrombosis and Cardiology. Dr. Spencer holds a Career Investigator Award from the Heart and Stroke Foundation.

Through the design and conduct of large observational studies, Dr. Spencer’s research is focused on improving our understanding of the current profile of patients at risk for arterial and venous disease and their complications as well as identifying and correcting deficiencies in timely diagnosis and management of these conditions. He is currently PI of the NIH-funded Worcester Venous Thromboembolism Study and the VENICE (Venous Thromboembolism in the Elderly: Natural History, Management, and Outcomes) Study. He is also co-PI of an NIH funded study of delay patterns in patients with heart failure.

Research Interests

Dr. Spencer’s research interests include the epidemiology of arterial and venous thrombotic diseases with a specific focus on utilization of evidence-based therapies.


Dr. Spencer holds a Career Award from the Heart and Stroke Foundation.

Selected Publications

1. Spencer FA, Ginsberg JS, Chong A, Alter DA. The relationship between unprovoked venous thromboembolism, age and acute myocardial infarction. J Thromb Haemost 2008;6:1507-1513

2. Spencer FA, Gore JM, Lessard D, Douketis JD, Emery C, Goldberg RJ. Outcomes after deep vein thrombosis and pulmonary embolism in the community: The Worcester Venous Thromboembolism Study. Arch Intern Med 2008;168(4):425-30

3. Spencer FA, Moscucci M, Granger CB, Gore JM, Goldberg RJ, Steg PG, Goodman SG, Budaj A, FitzGerald G, Fox KA; GRACE Investigators. Does comorbidity account for the excess mortality in patients with major bleeding in acute myocardial infarction? Circulation 2007;116:2793-2801.

4. Spencer FA, Goldberg RJ, Lessard D, Emery C, Reed G. Venous thromboembolism in the outpatient setting. Arch Intern Med 2007;167:1471-5.

Lab Profiles

Nima Vaezzadeh, PhD Candidate
Ran Ni, PhD Candidate
Shana Aadl Shaya, MSc Candidate

Lab Profiles

Kim Nagel, Clinical Research Coordinator
Helen Atkinson, Research Assistant
Netnapha Paredes, Research Assistant
Laura Calvert, MSc Candidate
Gabriela Chang, MSc Candidate
Sajjad Afraz, MSc Candidate