Paul Kim

Paul Kim

PhD, Queen's University, Kingston, Ontario

Assistant Professor

email: Paul.Kim@taari.ca

Education and Professional Standing

Dr. Kim earned his B.Sc.H. from Queen’s University, Kingston, Canada. He also earned his M.Sc. and Ph.D. from Queen’s University under the guidance of Dr. Michael Nesheim, a biophysical chemist. He has completed his Postdoctoral Fellowship at McMaster University under the supervision of Drs. Jeffrey Weitz and Peter Gross. During this time, Dr. Kim has focused his research in the field of thrombosis and hemostasis, specializing in protein-protein interactions and biophysical chemistry. He is currently serving as the co-chairman of the International Society on Thrombosis and Haemostasis (ISTH) Scientific and Standardization Committee (SSC) on Fibrinolysis.

Research Interests

Dr. Kim’s research focuses mainly in the biochemistry of blood coagulation and fibrinolysis, identifying and characterizing various molecular mechanisms of hemostasis. Current proteins of interest include plasminogen, fibrinogen, thrombin-activatable fibrinolysis inhibitor (TAFI), and coagulation factor V(a). To date, he has over 20 peer-reviewed publications and has been funded by various peer-reviewed grants such as CIHR and the Heart and Stroke Foundation of Canada.

Selected Publications

  1. Kim, P.Y., Vu, T.T., Leslie, B.A., Stafford, A.R., Fredenburgh, J.C., Weitz, J.I. (2014) Reduced plasminogen binding and delayed activation render y’-fibrin more resistant to lysis than yA-fibrin. J Biol Chem. 289(40), 27494-503.
  2. Kim, P.Y., Kim, P.Y.G., Taylor, F.B. Jr., Nesheim, M.E. (2012) Thrombin-activatable fibrinolysis inhibitor is activated in vivo in a baboon model of Escherichia coli induced sepsis. J Thromb Thrombolys. 33(4), 412-5.
  3. Kim, P.Y., Tieu, L.D., Stafford, A.R., Fredenburgh, J.C., Weitz, J.I. (2012) A high affinity interaction of plasminogen with fibrin is not essential for efficient activation by tissue plasminogen activator. J Biol Chem. 287(7), 4652-61.

Lab Profiles

Ji Zhou, MD, Research Associate
Jim Fredenburgh, PhD, Research Associate
Iqbal Jaffer, MBBS, MD Fellow, PhD
Tammy Truong, MSc, PhD Candidate
Vishal Patel, MSc Candidate
Alan Stafford, MSc, Research Assistant- Retired
Beverly Leslie, Research Assistant - Retired

Lab Profiles

Nima Vaezzadeh, PhD Candidate
Ran Ni, PhD Candidate
Shana Aadl Shaya, MSc Candidate

Lab Profiles

Dhruva Dwivedi, PhD, Research Associate
Ellen McDonald, Research Coordinator
Peter Grin, MSc Candidate
Neha Sharma, MSc Candidate
Nicole Zytaruk, RN, Research Coordinator

Lab Profiles

Kim Nagel, Clinical Research Coordinator
Helen Atkinson, Research Assistant
Netnapha Paredes, Research Assistant
Laura Calvert, MSc Candidate
Gabriela Chang, MSc Candidate
Sajjad Afraz, MSc Candidate